JCM Catalogue

Clostridium difficile (Hall and O'Toole 1935) Prévot 1938
Taxonomy in NCBI database: Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae.
1296 <-- ATCC 9689 <-- F. E. Clark 90556-M6S (L. S. McClung 1780).
Accessioned in 1982.
=ATCC 9689 =BCRC 10642 =CCUG 4938 =CECT 531 =CIP 104282 =DSM 1296 =LMG 15861 =LMG 21717 =NCIMB 10666 =NCTC 11209.
Clostridium difficile.
Type strain [596,11120,11273].
Medium: 13, 14;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +  Full / Short version of the cataloguepage top

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Source: Human feces [11120].
Biochemistry/Physiology: [11120].
Cell wall: meso-A2pm [11120].
Fatty acid: [1386,11120].
Phylogeny: 16S rRNA gene (AB075770, AB548672, X73450) [3374,11120].
Other taxonomic data: Protein profile [2652]; Antimicrobial susceptibility [1378].
Taxonomy: [11120].
Genome sequence: CP011968, CP011969 (plasmid) [10742].
More information: Metabolism of amino acids [1423].
NCBI Assembly ID: GCA_001077535 (GenBank), GCF_001077535 (RefSeq).
BacDive ID: 2582.
NCBI Taxonomy ID: 1496.
Genomic DNA is available from RIKEN BRC-DNA Bank: JGD12760.
Publication(s) using this strain [A04184, A06033, A06045, A09019, A09238, A10249, A11028, A11076, A11280, A12071, A13500, A15197, A15555, A17481, A18129, A18166, A20095, A20173, A20446, A20480, A21209, A22109, A23013, A23499].
Patent publication(s) using this strain [JP2008-143793A, JP2008-271931A, JP2008-199929A, WO2012/132913, WO2014/061752, 2015-164416, AU2015215750, 2016-169378, 2017-019833, WO2017/073753, 2021-40614].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5243 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
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Phylogeny: 16S rRNA gene (AB632374).
More information: MGH (Massachusetts General Hospital) strain No. 51.
BacDive ID: 165126.
Publication(s) using this strain [A20095, A22109, A23499].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5244 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632375).
More information: MGH (Massachusetts General Hospital) strain No. 53.
BacDive ID: 165127.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5245 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632376).
More information: MGH (Massachusetts General Hospital) strain No. 55.
BacDive ID: 165128.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5246 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632377).
More information: MGH (Massachusetts General Hospital) strain No. 57.
BacDive ID: 165129.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5247 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632378).
More information: MGH (Massachusetts General Hospital) strain No. 59.
BacDive ID: 165130.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5248 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
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Phylogeny: 16S rRNA gene (AB632379).
More information: MGH (Massachusetts General Hospital) strain No. 72.
BacDive ID: 165131.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5249 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632380).
More information: MGH strain (Massachusetts General Hospital) No. 74.
BacDive ID: 165132.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5250 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632381).
More information: MGH (Massachusetts General Hospital) strain No. 76.
BacDive ID: 165133.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5251 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632382).
More information: MGH (Massachusetts General Hospital) strain No. 78.
BacDive ID: 165134.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5252 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632383).
More information: MGH (Massachusetts General Hospital) strain No. 80.
BacDive ID: 165135.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5253 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632384).
More information: MGH (Massachusetts General Hospital) strain No. 82.
BacDive ID: 165136.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5254 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632385).
More information: MGH (Massachusetts General Hospital) strain No. 84.
BacDive ID: 165137.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5256 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632386).
More information: MGH (Massachusetts General Hospital) strain No. 88.
BacDive ID: 165138.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5257 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632387).
More information: MGH (Massachusetts General Hospital) strain No. 90.
BacDive ID: 165139.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
5258 <-- M. Seki <-- Meiji Seika Kaisha, Ltd.
Accessioned in 1985.
Clostridium difficile.
Medium: 14, 84;  Temperature: 37°C; Anaerobic; Rehydration fluid: 663.   more information +
Phylogeny: 16S rRNA gene (AB632388).
More information: MGH (Massachusetts General Hospital) strain No. 92.
BacDive ID: 165140.
Publication(s) using this strain [A20095].
 Related information on delivery / use of the strain
Biosafety level 2
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
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