JCM Catalogue

Streptomyces clavuligerus Higgens and Kastner 1971

Taxonomy in NCBI database: Bacteria; Actinobacteria; Actinomycetia; Streptomycetales; Streptomycetaceae.

4710T <-- KCC S-0710 <-- Tanabe Seiyaku Co., Ltd., Japan; MCRL 0774 <-- NRRL 3585 <-- Eli Lilly & Co., USA.
Accessioned in 1983.
=ATCC 27064 =BCRC 11518 =CBS 226.75 =CECT 3125 =CGMCC 4.1611 =DSM 738 =DSM 40751 =IFO 13307 =IMET 43657 =KCTC 9095 =MTCC 1142 =NBIMCC 3333 =NBRC 13307 =NCIMB 12785 =NCIMB 14335 =NRRL 3585 =VKM Ac-602.
Type strain [803].
Medium: 66;  Temperature: 28°C; Rehydration fluid: 656.

Source: Soil, South America [803].
Biochemistry/Physiology: [803].
Numerical taxonomy: [2933].
Quinone: MK-9(H8), MK-9(H6) [2332].
G+C (mol%): 72.5 (genome sequence) [12227].
Phylogeny: 16S rRNA gene (AB045869, AB184343, AY999718).
Genome sequence: ABJH00000000, CM000913, CM000914 (plasmid pSCL4), CM001015, CM001016 (plasmid pSCL1), CM001017 (plasmid pSCL2), CM001018 (plasmid pSCL3), CM001019 (plasmid pSCL4) [8874,8937], CP027858, CP027859 (plasmid pCLA1).
Production: Cephalosporins, penicillin N [803,4469] and clavulanic acid.
Application: Cyclization of phenylacetyl-L-cysteinyl-D-valine to benzylpenicillin using cell-free extracts [4471].
NCBI Assembly ID: GCA_000163875 (GenBank), GCF_000163875 (RefSeq).
BacDive ID: 15101.
NCBI Taxonomy ID: 1901.

Publication(s) using this strain [A10312, A21465].
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)

Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
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