JCM Catalogue

Lactobacillus casei subsp. rhamnosus Hansen 1968
Taxonomy in NCBI database: Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae.
1136 <-- ATCC 7469 <-- F. M. Strong (Lactobacillus casei).
Accessioned in 1982.
=ATCC 7469 =BCC 49729 =BCRC 10940 =CCM 1825 =CCUG 21452 =CECT 278 =CIP A157 =DSM 20021 =IAM 1118 =IFO 3425 =KCTC 1046 =LMG 6400 =NBRC 3425 =NCAIM B.01147 =NCCB 46033 =NCFB 243 =NCIMB 6375 =NCTC 12953 =NRIC 1043 =NRRL B-176 =NRRL B-442 =VKM B-574.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Type strain [596,12937].
Medium: 1;  Temperature: 37°C; Rehydration fluid: 663.   more information +  Full / Short version of the cataloguepage top

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Cell wall: [010].
G+C (mol%): 47.0 [053], 46.7 (genome sequence) [12937].
DNA-DNA relatedness: [012].
Phylogeny: 16S rRNA (M58815), 16S rRNA gene (D16552, LC145553) [2983], recA (AJ286117) [5363].
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Genome sequence: AZCQ00000000 [12937], PKQF00000000.
Assay: Folic acid [599], riboflavin [590], panthothenic, nicotinic and glutamic acids, pyridoxal and arginine [601], azothiopurine and 6-mercaptopurine.
NCBI Assembly ID: GCA_001435405 (GenBank), GCF_001435405 (RefSeq).
BacDive ID: 6427.
NCBI Taxonomy ID: 47715.
Genomic DNA is available from RIKEN BRC-DNA Bank: JGD12487.
Publication(s) using this strain [A04059, A04154, A04172, A04226, A05019, A06220, A07223, A08246, A09198, A09228, A10247, A11280, A12061, A12354, A12392, A13127, A14450, A16159, A16535, A18133, A18143, A19161, A21001, A21116, A21436, A22029, A22196, A23002, A23396, A23456, A24048, A24152, A24183, A24335, A24346, A24389, A24451].
Patent publication(s) using this strain [JP2007-112805A, JP2007-084533A, JP2007-284449A, JP2007-028920A, WO2007/013426, JP2008-074768A, WO2008/130036, JP2008-048652A, JP2008-271955A, US 20090111103 B2, JP2010-173984A, JP2012-205539A, WO2012/091081 , JP2014-003929A, WO/2014/171478 , 2015-86214, CN106173246, 2016-208996, 2016-073314, 2016-037451, 2017-201984, WO2017/026481, 2019-77694, 2020-132560, 7076840, 2022-183435, 2022-33444, WO2022-202372, WO2022-137644, WO2022-039249, WO2023-277041, 2023-128589, 2023-150100, 2023-152713, 2023-159522, 2023-33337, 2023-58649, P2024-32856A].
 Related information on delivery / use of the strain
Biosafety level 1 -
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
1165 <-- T. Mitsuoka S8-8 <-- DSM 20022 <-- ATCC 7469a <-- M. Goulian (Lactobacillus casei) <-- V. Herbert <-- H. Baker <-- ATCC 7469 <-- F. M. Strong.
Accessioned in 1982.
=ATCC 7469a =DSM 20022 =NCIMB 10023.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 37°C; Rehydration fluid: 663.   more information +
Cell wall: [587].
DNA-DNA relatedness: [012].
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
Assay: Folic acid.
BacDive ID: 6428.
Publication(s) using this strain [A12354].
 Related information on delivery / use of the strain
Biosafety level 1 -
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
1553 <-- ATCC 11443 <-- M. Brin (Lactobacillus delbrueckii).
Accessioned in 1982.
=ATCC 11443 =BCRC 12321.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 37°C; Rehydration fluid: 663.   more information +
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DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
Genome sequence: CP022109.
Production: L-(+)-Lactic acid [617].
Assay: Optically active isomers of lactic acid [342].
NCBI Assembly ID: GCA_003433395 (GenBank), GCF_003433395 (RefSeq).
BacDive ID: 161603.
Publication(s) using this strain [A12354, A18498].
 Related information on delivery / use of the strain
Biosafety level 1 -
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
1561 <-- ATCC 9595 <-- Merck & Co., Inc.; 4R2127 (Lactobacillus casei) <-- I. C. Gunsalus <-- U. Wisconsin.
Accessioned in 1982.
=ATCC 9595 =ATCC 11979 =BCRC 11673 =BUCSAV 226 =CCM 1828 =CECT 288 =CIP 57.6 =DSM 20245 =NCFB 207 =NCIMB 7473 =NCIMB 8019 =NCTC 7473 =VKM B-575.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 37°C; Rehydration fluid: 663.   more information +
G+C (mol%): 45.8 (Tm) [011].
DNA-DNA relatedness: [012].
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
Assay: Serine, aspartic and glutamic acids [621].
BacDive ID: 6430.
Publication(s) using this strain [A11232, A12354, A13127].
 Related information on delivery / use of the strain
Biosafety level 1 -
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
1563 <-- ATCC 27773 <-- R. E. Davis 9782.
Accessioned in 1982.
=ATCC 27773.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 37°C; Rehydration fluid: 663.   more information +
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DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
Assay: Folic acid [622].
BacDive ID: 161612.
Publication(s) using this strain [A12354, A13127].
Patent publication(s) using this strain [JP2008-206516A].
 Related information on delivery / use of the strain
Biosafety level 1 -
Terms and conditions Not applicable -
Export control (1) No -
Distribution control in Japan (2) No -
Genetically modified microorganism No -
Technical information - -
Additional information - -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
2771 <-- M. Seki M35 <-- S. Tanasupawat.
Accessioned in 1984.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 35°C; Rehydration fluid: 663.   more information +
Source: Fermented molasses.
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
BacDive ID: 163408.
Publication(s) using this strain [A11048, A12354].
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
2772 <-- M. Seki M52 <-- S. Tanasupawat.
Accessioned in 1984.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 35°C; Rehydration fluid: 663.   more information +
Source: Fermented molasses.
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
BacDive ID: 163409.
Publication(s) using this strain [A12354, A22523].
Patent publication(s) using this strain [JP2007-028920A, JP2011-223910A].
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
8134 <-- NCFB 244 <-- NCTC 6557 <-- M. E. Sharpe <-- NIRD <-- E. Davis.
Accessioned in 1991.
=ATCC 11981 =CCM 1836 =NCFB 244 =NCIMB 6557 =NCTC 6557 =VKM B-577.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 30°C; Rehydration fluid: 663.   more information +
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Source: Milk products.
Biochemistry/Physiology: [2833].
DNA-DNA relatedness: [2833].
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
BacDive ID: 165744.
Publication(s) using this strain [A12354, A13127].
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
8135 <-- NCFB 252 <-- M. E. Sharpe <-- NIRD <-- Res. Assoc. of Birt. Flour Millers.
Accessioned in 1991.
=ATCC 11982 =NCFB 252 =NCIMB 8103.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 30°C; Rehydration fluid: 663.   more information +
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Source: Milk products.
Biochemistry/Physiology: [2833].
DNA-DNA relatedness: [2833].
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
BacDive ID: 148014.
Publication(s) using this strain [A12354, A13127].
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
8136 <-- NCFB 1051 <-- A. C. Hayward <-- Birmingham Univ.
Accessioned in 1991.
=NCFB 1051.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
"Lactobacillus casei subsp. plantarum".
Medium: 1;  Temperature: 30°C; Rehydration fluid: 663.   more information +
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Source: Milk products.
DNA typing: Ribotype [4925].
Other taxonomic data: MALDI-TOF MS [9228].
Taxonomy: [12937].
BacDive ID: 165745.
Publication(s) using this strain [A12354].
Patent publication(s) using this strain [JP2007-112805A, JP2009-195251A].
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
8602 <-- M. Seki M27 <-- S. Tanasupawat.
Accessioned in 1992.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 1;  Temperature: 30°C; Rehydration fluid: 663.   more information +
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Source: Fermented cane molasses [3244].
Biochemistry/Physiology: [3244].
Phylogeny: 16S rRNA gene (AB690191).
Taxonomy: [12937].
BacDive ID: 165848.
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
8649 <-- M. Seki M84 <-- S. Tanasupawat.
Accessioned in 1992.
Lactobacillus rhamnosus.
Lactobacillus casei subsp. rhamnosus.
Medium: 13;  Temperature: 30°C; Rehydration fluid: 663.   more information +
Source: Fermented cane molasses [3244].
Biochemistry/Physiology: [3244].
Phylogeny: 16S rRNA gene (AB690234).
Taxonomy: [12937].
BacDive ID: 165893.
 Related information on delivery / use of the strain
Biosafety level 1
Terms and conditions Not applicable
Export control (1) No
Distribution control in Japan (2) No
Genetically modified microorganism No
Technical information -
Additional information -
 (1) in complying with the Foreign Exchange and Foreign Trade Control Law of Japan
 (2) in complying with the Plant Protection Law of Japan

 Delivery category
Domestic A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Overseas A (Freeze-dried or L-dried culture) or C (Actively growing culture on request)
Viability and purity assays of this product were performed at the time of production as part of quality control. The authenticity of the culture was confirmed by analyzing an appropriate gene sequence, e.g., the 16S rRNA gene for prokaryotes, the D1/D2 region of LSU rRNA gene, the ITS region of the nuclear rRNA operon, etc. for eukaryotes. The characteristics and/or functions of the strain appearing in the catalogue are based on information from the corresponding literature and JCM does not guarantee them.
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